Recruitment and Function in Mice Kinase AKT1 Negatively Controls Neutrophil
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چکیده
Print ISSN: 0022-1767 Online ISSN: 1550-6606. Immunologists, Inc. All rights reserved. Copyright © 2013 by The American Association of 9650 Rockville Pike, Bethesda, MD 20814-3994. The American Association of Immunologists, Inc., is published twice each month by The Journal of Immunology at U niersity of N rth D aota L ib of H ealth Scences on O cber 9, 2013 hp://w w w jim m unl.org/ D ow nladed from
منابع مشابه
Synthesis and Docking Analysis of New Heterocyclic System N1, N4-bis ((2-chloroquinolin-3-yl) methylene) benzene-1, 4-diamine as Potential Human AKT1 Inhibitor
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The Akt family of serine/threonine kinases includes Akt1, Akt2, and Akt3 isoforms. Prior studies have reported that Akt1 and Akt2, but not Akt3, are expressed in platelets. Here, we show that Akt3 is expressed in substantial amounts in platelets. Akt3(-/-) mouse platelets selectively exhibit impaired platelet aggregation and secretion in response to low concentrations of thrombin receptor agoni...
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